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Retatrutide LY-3437943 For Weight Loss 15mg * 10vials * 1kits

Retatrutide LY-3437943 For Weight Loss 15mg 10vials

Original price was: $2,000.00.Current price is: $600.00.

Retatrutide (LY3437943) is an agonist of the glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and glucagon receptors.

The data from the trials mentioned that Retatrutide is effective in reducing weight in individuals with nonsyndromic obesity.

Retatrutide LY-3437943 For Weight Loss 15mg * 10vials * 1kits

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Description

Retatrutide LY-3437943 For Weight Loss 15mg * 10vials * 1kits

Retatrutide (LY3437943) is an agonist of the glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and glucagon receptors. It is a single peptide conjugated to a lipid diacid molecule, exerts a powerful agonist effect on the human glucagon‐receptor (GCGR), GIPR, and GLP‐1R.

In comparison with the human glucagon and glucagon‐like peptide 1 (GLP‐1), retatrutide exhibits reduced potency (by a factor of 0.3 and 0.4, respectively) on the GCGR and GLP‐1R, while displaying enhanced potency at the human GIPR (by a factor of 8.9) when compared to the glucose‐dependent insulinotropic polypeptide (GIP).In vitro, Retatrutide demonstrates similar efficacy to natural glucagon in evoking glucose production within hepatocytes. While in adipocytes, it surpasses native GIP in inducing lipolysis.

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